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A Blood-Based Biomarker Test Can Screen Alzheimer’s Disease Early, Allowing for Timely Treatment

A Class of Combined Treatments for Airfoil Trailing Edge Noise Mitigation

A Clinical Proven Biologics, SGC, for Unmet Life-threatening Medical Need on Skin Regeneration

A Method for Lithium Resources Extracting from Retired Lithium-ion Battery Wastes

A Multifunctional Bioprinting Platform for Next-Generation Synthetic Tissues

A New Treatment for Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) Targets G4C2 DNA and RNA Tandem Repeats Using Selective Small Molecules

A Revolutionary Approach to Develop Innovative Anticancer Drugs Targeting DNA Replication-Initiation Proteins

A Solar Control Film for Glass Window, that Blocks Heat and UV While Maintaining High Visibility and RF/WiFi Transmission

A Time-and-Energy-Efficient Ising Computer for Portfolio Optimization and Risk Management

AAV – Gene Therapy Delivery Platform for Treatment of Brain Diseases

Acoustic Metamaterials: Next-Generation Noise Control and Audio Solution

Adsorbents for Ambient Temperature NO2 Removal and Their Application on Health-Focused Air Purification

Advanced Organic Photovoltaic (OPV) Materials

Advanced Polymer-Based Therapeutics for Chronic Diseases

AeroLink: Low Altitude UAV Long-Range Remote ID and Control System

AI Agents Based on Large Language Model

AI Tower Crane System

AI-Blockchain Enabled Decentralized Art Title, Asset Authentication & Management Platform

AI-DTCO (AI-empowered Design Technology Co-Optimization)

AI-Enabled Development of Tissue/Cell-Specific AAV Capsids for Therapeutic Delivery

AI-Enabled Medical Imaging for Next-Gen Histological Imaging

AI-Enabled Non-Invasive Pulmonary Hypertension Hemodynamics Assessment Using Multi-Modal Echocardiography

Amplicon Contamination-Depleted CRISPR/Cas-Regulated Isothermal Molecular Assay at Skin Temperature

An Integrative System for food 3D Printing and Multi-Level Cooking for Making Personalized Meals with Ease

An Open Peer-to-Peer Edge Computing Platform for AI-as-a-Service

Articulated Cycling Mannequin for Wind Tunnel Testings

BioEnergyCrete+: Carbon-Neutral 3D Biochar-Concrete Printing with Energy Storage

Biomaterial-Based Artificial Cells for Transforming Cell & Gene Therapy Outcomes

Blood Protein Biomarkers for Early Detection and Treatment of Neurodegenerative Diseases

Branching in Instant Tissue Adhesives for Softer Mechanical Properties

Breakthrough from Zero: Ultra-Early Blood Screening for Colorectal Cancer

Cementless Lightweight Materials from CO2-Sequestering Waste Mixtures for Sustainable Construction

Collaborative and Personalized Digital Twin Platform for Smart Facility Operation Management

Consumer-Level Spectral Sensing for Food Quality, Safety, and Nutrition Analysis

Development and Commercialization of Bionic Olfactory Chips and System

Development of Anti-Angiogenic Eyedrop for Eye Disease

Digital Twin of Regional Earth System in the GBA

DMCC: An Environmental Friendly API Purification System

DreamOmni2: Multimodal Instraction-Based Editing and Generation

Drug Development for CNS Regeneration

Efficient Inference Accelerator for Large AI Model

Electrochemically-Cycled Oxidation (ECO)®

Electronic Design Automation (EDA) for Many-Cores Deep Learning Accelerator Design

Elimination of Grain Surface Concaves in Metal Halide Perovskite Films for Improved Solar Cells

Energy Conversion from Waste Heat to Electricity by Giant Pyroelectric Effect

Energy-Efficient Optical PCIe/CXL Chipsets and Co-Packaged Optics (CPO) for AI Data Centers

Epitaxial Growth of Mixed-Dimensional Heterostructures for High-Efficient Self-Powered Photodetector

Fast Sparse-View Cone-Beam CT Reconstruction Method for Reduced Radiation

Follow-Your-Emoji-Faster: Towards Efficient, Fine-Controllable, and Expressive Freestyle Portrait Animation

Gene Editing for Familial Alzheimer’s Disease (FAD) Treatment

Germline Genome AluScan: Cost-Effective First-line Prediction of Cancers and Complications

Green Antifouling Solutions Based on Patented Butenolide Technology

Green Sound Insulation Panels

Green Strategy For Body Cooling: Radiative Cooling Metamaterial Fabrics

Green-House-Gas-Free Elastocaloric Cooling/ Heating Technology – Materials and Devices

Hardware Accelerator for Financial Computing

Heterogeneous Multi-Robot Systems for Marine Monitoring

High Performance and Long Durability Pd@Pt Core-Shell Fuel Cell Catalysts

High-Energy, Safe Solid-State Lithium Batteries

High-Performance Condensers Utilizing Triply Periodic Minimal Surface Structures

High-Performance Polymer-Based Quasi-Solid Electrolytes for Commercial High-Energy-Density Batteries

High-performance Specialized Digital Sensor Chip for IoE Era

High-Throughput AI-based Screening Platform for Drug Discovery

HKGAI: Build sovereign generative artificial intelligence models and boost Hong Kong’s role as a global AI development hub

Home-Based Home Healthcare Management for COPD Patients

Innovative Full-Color Micro-LED Micro-Display: A Revolutionary Technology for AR/XR Industry

IoT and Sensing Technologies for Smart City Applications

Key Algorithms and Software for the Aerodynamics of Electric Vehicles

Knowledge-as-a-Service Powered by Privacy-Enhanced Distributed LLM

LightSkin: Flexible Optical Tactile Skin for High-Resolution Robotic Perception

Low Energy Electrical Odor Control of Sludge: LEEO®

MarineInst: A Foundation Model for Marine Image Analysis with Instance Visual Description

Mask-free Material Deposition on Arbitrary Substrate by Direct Laser Writing

Massively Parallel High-Throughput Multi-Omic Single-Cell Sequencing for Target Discovery

Material Innovations for a Sustainable World

Method for In-Situ Synthesis of Perovskite within the Pores of a Porous Membrane

MeticTouch – Non-invasive Ultrasound Ocular Drug Delivery Platform

MGM-Omni: Scaling Omni LLMs to Personalized Long-Horizon Speech

Micro-second Response Ferroelectric Liquid Crystal (FLC) Light Modulator for Time-Sequential-Multiplexed 3D, Vivid-Color Display, and Wavelength Selective Switch (WSS)

Microcapsule Technologies for High Value-Added Industrial Adhesives

ModeIO: A Privacy, Compliance and Safety Infrastructue for AI Product and Data Flow

Monolithically Integrated Analogue Neuromorphic Network Based on Parallel-Connected Dual Gate Metal-Oxide Thin Film Transistor

Multi-Functional Green Coating Materials for Sustainable Glazing Surface

Nano Positioning Stage for Applications under Extreme Environmental Conditions

Natural Herbal Products for Treating Memory Loss and Neuronal Degeneration

NCDriskClear AI™: Closed-Loop NCD Risk Clearance & Treatment Guidance

Next-Generation Lithium Metal Batteries with Ultra-High Nickel Cathode Material

Non-Tolerance Type-11/2 ALK Inhibitor for Cancer Treatment

Novel Automative Ways For Atmospheric Monitoring

OmniBP: Building a Continuous, Cuffless, and Reliable Blood Pressure Ecosystem

On-Site Microplastic Detection for Rapid and Accurate Waste Effluent Analysis

Optima AI: AI-Native Conversational E-Commerce Platform

Painless Microneedles for Transdermal Drug Delivery

Perovskite-Based Next-Gen Visual Sensors for AI Perception

Personalized Real-Time Air Quality Informatic System for Exposure – Hong Kong (PRAISE-HK)

Photo-Aligned Multi-Domain Vertical Alignment LCD for Cost Effective Mass Production with Existing Equipment

Photoelectrochemical (PEC) System for Low-Carbon- Emission Saline Sewage Treatment Coupled with Green

Physics-Constrained Dictionary Learning for Medical Image Compression and Denoising

Polymeric Hole Transporting Layers for Cost-Effective and Stable Perovskite Solar Cells

Portable and Wireless Real-time Adaptive Traffic Signal Control System for Temporary Traffic Arrangements

Portable Device for Quick DNA Testing Using CRISPR/Microfluidic Technology

Privacy-enhanced Business Intelligence Platform

Project Feilian: Next-Gen AI Cost Effective Hyperspectral Remote Sensing Satellite Constellation

Q-Blimp: A Human-friendly Quiet Autonomous Blimp

Quantitative Subsurface Defect Characterization in Granular Systems for Energy Applications Using a Robust Machine Learning-Based Active Thermography

Quantum Rod LEDs for Display and Lighting with High Quantum Yield and Tunable Wavelength of Emission

Redefining Wearables: Skin Patch Sweat Sensor for Non-Invasive & Continuous Health Monitoring

Revolutionizing Energy Storage: Tube Transport-Inspired All-Solid-State Electrolytes for Li-Based Batteries

Safe and Affordable Energy Storage enabled by Self-Organized Metallic Nanostructure

SANI® Process – A Paradigm – Shift Sewage Treatment Technology with a 70% Reduction of Sludge

Secretion-Management Targeted Skin Cancer Treatment

Smart EcoClean Matrix

Smart Home Irrigation Solution

Smart Polymer Processing Plant (S-P3) – Open Collaborative Intelligent Platform

SMARTCARE – AI Powered Consultation & Medical Education System

SmartPath – A Full-stack Large AI Model-driven Computational Pathology Platform for Precision Oncology

SnowEdge: AI-empowered Digital Snowboarding Coach

SOSA® | Sulfidogenic Oxic-Settling Anaerobic Technology

Specializing in Ocular Health, Offering a Hot-Yoga Goggle Device to Relieve Dryness and Protect Against Glaucoma, Along with a Mobile App for Early Detection of Ocular Diseases

Strength in Thinness: Ultra-Strong Polymer Nanofilm for Cutting-Edge Applications

System for Freeze Desalination of Seawater

The Cost-Effective 3D Tactile Solution for humanoid Robotics & Smart Devices

Thermal Shielding and Vapor Permeable MOF-Enabled Nanofiberic Membrane (MEM)

Time-Reversal Diagnostic for the Health Monitoring of Pressurized Pipelines

Triple the mRNA Vaccine Efficacy Via Tailored Tail Sequence

Ultrasonic Phased Array System for Battery Inspection

Visible Light-Controllable Hemostatic Bioglue

VisionReasoner: Unified Reasoning-Integrated Visual Perception Model

Wi-Fi Only Indoor Localization System

Wireless and Self-powered Sensor System

Zero Carbon GelSoap for a Healthy and Sustainable Living Style

Zonic Story-Cut Agent – Learnable Agentic AI for Fluent Storytelling Rough Cuts

Blood Protein Biomarkers for Early Detection and Treatment of Neurodegenerative Diseases

Technology ID

TT-0108

Description

This technology discovers and validates blood biomarkers for the early detection and progression monitoring of neurodegenerative diseases, creating opportunities for improved diagnosis and therapeutic development.

Content

Discovery Platform: Human bio-data analytics enable systematic identification of novel blood biomarkers and their regulatory pathways Biological Validation: Preclinical studies in human cells and mouse models confirm the functional relevance of candidate biomarkers Translation Capability: Established platforms exist for developing therapeutic modalities targeting identified pathways, with preliminary drug hits available for selected targets Clinical Utility Potential: Blood biomarkers support diagnostics, prognosis, and drug-response monitoring, creating opportunities for personalized treatment strategies

Inventors

Prof. Nancy IP

Applicable Industries

Education, Research, and Professional Services

Biomedical, Healthcare and Food

Potential Application

Data Science

Drug Discovery

Diagnostics

Alzheimer's disease biomarkers

Technology Focus

Medical and Biotechnology